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Found 6 results

  1. Version 1.0.0

    1 download

    This model is the bilateral thigh skin rendering of a 56 year old male with a pleomorphic leiomyosarcoma of the anterior compartment of the right thigh. The patient underwent neoadjuvant radiotherapy, surgery, and adjuvant chemotherapy treatment and was found to have an intermediate grade lesion at the time of diagnosis. However, the tumor metastasized to his lungs, and the patient died 2.5 years after diagnosis. This is an STL file created from DICOM images of his CT scan which may be used for 3D printing. Leiomyosarcomas are aggressive soft tissue malignancies that are thought to arise from the smooth muscle cells lining small blood vessels. Pleomorphism is the pathologic description of cells and nuclei with variability in size, shape and staining, which is characteristic of a malignant neoplasm. Pleomorphic leiomyosarcoma is an aggressive form of leiomyosarcoma, accounting for approximately 10% of these tumors. The mean age of occurrence is 58 years old, with a range from 31-89 years. These usually occur in the extremities, but may also present in the retroperitoneum/abdominal cavity, chest/abdominal wall, and, occasionally, the scalp. On biopsy, the definition of pleomorphic leiomyosarcoma is the presence of pleomorphic cells in at last two-thirds of the cut section and at least one section of positive staining for smooth muscle. Treatment is early wide resection of the primary lesion and neo-adjuvant or adjuvant chemotherapy and radiation. Tumors may metastasize to the lung. A large primary tumor and presence in the retroperitoneal cavity are poor predictive factors, and about 65% of patients succumb to the disease. This model was created from the file STS_014.

    Free

  2. Version 1.0.0

    2 downloads

    This model is the bilateral thigh muscle rendering of a 56 year old male with a pleomorphic leiomyosarcoma of the anterior compartment of the right thigh. The patient underwent neoadjuvant radiotherapy, surgery, and adjuvant chemotherapy treatment and was found to have an intermediate grade lesion at the time of diagnosis. However, the tumor metastasized to his lungs, and the patient died 2.5 years after diagnosis. This is an STL file created from DICOM images of his CT scan which may be used for 3D printing. Leiomyosarcomas are aggressive soft tissue malignancies that are thought to arise from the smooth muscle cells lining small blood vessels. Pleomorphism is the pathologic description of cells and nuclei with variability in size, shape and staining, which is characteristic of a malignant neoplasm. Pleomorphic leiomyosarcoma is an aggressive form of leiomyosarcoma, accounting for approximately 10% of these tumors. The mean age of occurrence is 58 years old, with a range from 31-89 years. These usually occur in the extremities, but may also present in the retroperitoneum/abdominal cavity, chest/abdominal wall, and, occasionally, the scalp. On biopsy, the definition of pleomorphic leiomyosarcoma is the presence of pleomorphic cells in at last two-thirds of the cut section and at least one section of positive staining for smooth muscle. Treatment is early wide resection of the primary lesion and neo-adjuvant or adjuvant chemotherapy and radiation. Tumors may metastasize to the lung. A large primary tumor and presence in the retroperitoneal cavity are poor predictive factors, and about 65% of patients succumb to the disease. This model was created from the file STS_014.

    Free

  3. Version 1.0.0

    5 downloads

    This model is the right thigh muscle rendering of a 56 year old male with a pleomorphic leiomyosarcoma of the anterior compartment of the right thigh. The patient underwent neoadjuvant radiotherapy, surgery, and adjuvant chemotherapy treatment and was found to have an intermediate grade lesion at the time of diagnosis. However, the tumor metastasized to his lungs, and the patient died 2.5 years after diagnosis. This is an STL file created from DICOM images of his CT scan which may be used for 3D printing. Leiomyosarcomas are aggressive soft tissue malignancies that are thought to arise from the smooth muscle cells lining small blood vessels. Pleomorphism is the pathologic description of cells and nuclei with variability in size, shape and staining, which is characteristic of a malignant neoplasm. Pleomorphic leiomyosarcoma is an aggressive form of leiomyosarcoma, accounting for approximately 10% of these tumors. The mean age of occurrence is 58 years old, with a range from 31-89 years. These usually occur in the extremities, but may also present in the retroperitoneum/abdominal cavity, chest/abdominal wall, and, occasionally, the scalp. On biopsy, the definition of pleomorphic leiomyosarcoma is the presence of pleomorphic cells in at last two-thirds of the cut section and at least one section of positive staining for smooth muscle. Treatment is early wide resection of the primary lesion and neo-adjuvant or adjuvant chemotherapy and radiation. Tumors may metastasize to the lung. A large primary tumor and presence in the retroperitoneal cavity are poor predictive factors, and about 65% of patients succumb to the disease. This model was created from the file STS_014.

    Free

  4. Version 1.0.0

    2 downloads

    These images are the isolated left thigh tumor muscle renderings of an 82 year old male with a dedifferentiated liposarcoma in the anterior compartment of the left thigh. This is an STL file created from DICOM images of his CT scan which may be used for 3D printing. Liposarcomas are the second most common soft tissue sarcoma in adults, occurring more commonly in males between the ages of 50 and 80 years old. They present as a slow growing, painless mass typically located in the extremities, with the thigh being the most common location. Multiple variants of liposarcomas exist, but the dedifferentiated type is a high-grade sarcoma. Dedifferentiated liposarcomas are typically located adjacent to a well-differentiated lipomatous lesion. The incidence of pulmonary metastasis increases with grade. Therefore, work up of the lesion consists of MRI, biopsy through the area of future resection, CT of the chest, abdomen and pelvis to rule out metastases. Treatment consists of radiation and wide surgical resection but chemotherapy agents are being developed to target chromosomal abnormalities associated with certain well-differentiated and dedifferentiated liposarcomas. This patient received radiation and resection of the tumor and has not had a metastasis or recurrence in 4.5 years. This model came from the file STS_013.

    Free

  5. Version 1.0.0

    1 download

    These images are the bilateral leg muscle renderings of an 82 year old male with a dedifferentiated liposarcoma in the anterior compartment of the left thigh. This is an STL file created from DICOM images of his CT scan which may be used for 3D printing. Liposarcomas are the second most common soft tissue sarcoma in adults, occurring more commonly in males between the ages of 50 and 80 years old. They present as a slow growing, painless mass typically located in the extremities, with the thigh being the most common location. Multiple variants of liposarcomas exist, but the dedifferentiated type is a high-grade sarcoma. Dedifferentiated liposarcomas are typically located adjacent to a well-differentiated lipomatous lesion. The incidence of pulmonary metastasis increases with grade. Therefore, work up of the lesion consists of MRI, biopsy through the area of future resection, CT of the chest, abdomen, and pelvis to rule out metastases. Treatment consists of radiation and wide surgical resection but chemotherapy agents are being developed to target chromosomal abnormalities associated with certain well-differentiated and dedifferentiated liposarcomas. This patient received radiation and resection of the tumor and has not had a metastasis or recurrence in 4.5 years. This figure came from the file STS_013.

    Free

  6. Version 1.0.0

    17 downloads

    This image is the left thigh bone rendering of an 82 year old male with a dedifferentiated liposarcoma in the anterior compartment of the left thigh. This is an STL file created from DICOM images of his CT scan which may be used for 3D printing. Liposarcomas are the second most common soft tissue sarcoma in adults, occurring more commonly in males between the ages of 50 and 80 years old. They present as a slow growing, painless mass typically located in the extremities, with the thigh being the most common location. Multiple variants of liposarcomas exist, but the dedifferentiated type is a high-grade sarcoma. Dedifferentiated liposarcomas are typically located adjacent to a well-differentiated lipomatous lesion. The incidence of pulmonary metastasis increases with grade. Therefore, work up of the lesion consists of MRI, biopsy through the area of future resection, CT of the chest, abdomen, and pelvis to rule out metastases. Treatment consists of radiation and wide surgical resection but chemotherapy agents are being developed to target chromosomal abnormalities associated with certain well-differentiated and dedifferentiated liposarcomas. This patient received radiation and resection of the tumor and has not had a metastasis or recurrence in 4.5 years. This image came from the file STS_013.

    Free

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