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  1. The skin is the largest organ of the body and many researchers show interest on this particular organ as it serves as the body’s first line of defense against pathogens. The skin is made up of tissues that have a semi-permeable capacity. This means that it only allows certain substances in and keeps others out. The skin is considered as the most durable organ of the body that can withstand different types of elements. Cosmetic company L’ Oreal has teamed up with 3D printing company Organovo to create the first ever 3D printed skin. The company teamed up such that each will contribute something to the technology. For instance, Organovo will provide the bioprinter while L’ Oreal will provide the skin cell technology. However, the latter will have exclusive rights to the 3D printed skin tissues which the company will use to develop, test, manufacture as well as evaluate the efficacy of their skin care products. The creation of the 3D printed skin tissue will create a huge impact on the skin care industry. Conventionally, skin care companies test the efficacy as well as toxicity of their products on human or animal skin. This puts the health of the clinical subjects at risk especially for products that have never been tested before for toxicity. Aside from using the 3D printed skin to test skin care products, this technology has the potential to be used in skin-related surgical tests and studies. It is interesting to take note that 3D printing has gone a very long way since it was used in developing medical innovations. Hopefully, researchers will be able to develop more 3D bioprinted organs aside from skin.
  2. Conventional cosmetic testing is often done on animals. However, cosmetic testing on animals is very controversial thus a leading cosmetic company, L’Oreal invested on 3D bioprinted skin for safer cosmetic testing by partnering with a leading 3D bioprinting company. L’Oreal partnered with a 3D bioprinting company, Organovo, to create 3D bioprinted skin to test the toxicity of personal care products. The company has been developing the 3D printed skin since October this year. Organovo also announced the commercial release of this testing kit dubbed as exVive3D Human Liver Tissue. Organovo also partnered with the Yale School of Medicine’s Department of Surgery for the transplant of human patients who will be subjected to the clinical trials for five years. The exVive3D Human Liver Tissue used in preclinical drug testing works by replicating the functions of a living human liver tissue such as its ability to produce proteins. It is created to look like a skin. Testing run of the bioprinted tissue was able to differentiate toxic and non-toxic compounds. Moreover, the bioprinted liver also allows both histological and biochemical data to be collected thus customers can investigate the responses of compounds at multiple levels. Bioprinting can revolutionize conventional tissue engineering by addressing the shortage of available tissue for both transplantation and repair. However, what Organovo and L’Oreal did is that they took tissue bioprinting to the next level by finding novel application. This new application of 3D bioprinting has opened new doors on how to use 3D medical bioprinting to the next level.
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