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Found 180 results

  1. Version 1.0.0

    0 downloads

    The knee is the largest joint and one of the most important joints in the body. It plays an essential role in movement related to carrying the body weight in horizontal (running and walking) and vertical (jumping) directions. The knee joint joins the thigh with the leg and consists of two articulations: one between the femur and tibia (tibiofemoral joint), and one between the femur and patella (patellofemoral joint). The knee is a modified hinge joint, which permits flexion and extension as well as slight internal and external rotation. The knee joint is vulnerable to injury and to the development of osteoarthritis. The knee is composed of three functional compartments: the patellofemoral articulation, consisting of the patella, or "kneecap", and the patellar groove on the front of the femur through which it slides; and the medial and lateral tibiofemoral articulations linking the femur, or thigh bone, with the tibia, the main bone of the lower leg. The joint is bathed in synovial fluid which is contained inside the synovial membrane called the joint capsule. This is a 3D-printable medical STL file of normal right knee joint converted from a CT scan DICOM dataset of a 75-year old female patient(STS-016).

    Free

  2. Version 1.0.0

    0 downloads

    This is a case of left thigh posterior mass in a 75-year old female patient. Pathological examination of the specimen revealed spindle shaped cells suggestive of liposarcoma with intermediate grade of malignancy. MRI was done for this patient 33 days before taking the biopsy, and a week after confirming the diagnosis a PET scan was done as a part of the metastatic workup. After performing surgical resection of the tumor followed by radiotherapy, the patient showed no evidence of recurrence for 760 days of follow up. This is a 3D printable medical STL file converted from the real CT scan DICOM dataset of this patient(STS-016).

    Free

  3. Version 1.0.0

    1 download

    This model is the bilateral thigh skin rendering of a 56 year old male with a pleomorphic leiomyosarcoma of the anterior compartment of the right thigh. The patient underwent neoadjuvant radiotherapy, surgery, and adjuvant chemotherapy treatment and was found to have an intermediate grade lesion at the time of diagnosis. However, the tumor metastasized to his lungs, and the patient died 2.5 years after diagnosis. This is an STL file created from DICOM images of his CT scan which may be used for 3D printing. Leiomyosarcomas are aggressive soft tissue malignancies that are thought to arise from the smooth muscle cells lining small blood vessels. Pleomorphism is the pathologic description of cells and nuclei with variability in size, shape and staining, which is characteristic of a malignant neoplasm. Pleomorphic leiomyosarcoma is an aggressive form of leiomyosarcoma, accounting for approximately 10% of these tumors. The mean age of occurrence is 58 years old, with a range from 31-89 years. These usually occur in the extremities, but may also present in the retroperitoneum/abdominal cavity, chest/abdominal wall, and, occasionally, the scalp. On biopsy, the definition of pleomorphic leiomyosarcoma is the presence of pleomorphic cells in at last two-thirds of the cut section and at least one section of positive staining for smooth muscle. Treatment is early wide resection of the primary lesion and neo-adjuvant or adjuvant chemotherapy and radiation. Tumors may metastasize to the lung. A large primary tumor and presence in the retroperitoneal cavity are poor predictive factors, and about 65% of patients succumb to the disease. This model was created from the file STS_014.

    Free

  4. Version 1.0.0

    1 download

    This is the normal right foot and ankle bone model of a 56 year old male with right anterior thigh pleomorphic leiomyosarcoma. This is an STL file created from DICOM images of his CT scan which may be used for 3D printing. The ankle is a hinge (or ginglymus) joint made of the distal tibia (tibial plafond, medial and posterior malleoli) superiorly and medially, the distal fibula (lateral malleolus) laterally and the talus inferiorly. Together, these structures form the ankle “mortise”, which refers to the bony arch. The normal range of motion is 20 degrees dorsiflexion and 50 degrees plantarflexion. Stability is provided by the anterior talofibular ligament (ATFL), calcaneofibular ligament (CFL), and posterior talofibular ligament (PTFL) laterally, and the superficial and deep deltoid ligaments medially. The ankle is one of my most common sites of musculoskeletal injury, including ankle fractures and ankle sprains, due to the ability of the joint to invert and evert. The most common ligament involved in the ATFL. The foot is commonly divided into three segments: hindfoot, midfoot, and forefoot. These sections are divided by the transverse tarsal joint (between the talus and calcaneus proximally and navicular and cuboid distally), and the tarsometatarsal joint (between the cuboids and cuneiforms proximally and the metatarsals distally). The first tarsometatarsal joint (medially) is termed the “Lisfranc” joint and is the site of the Lisfranc injury seen primarily in athletic injuries. This model was created from the file STS_014.

    Free

  5. Version 1.0.0

    1 download

    This is the normal left foot and ankle muscle model of a 56-year-old male with right anterior thigh pleomorphic leiomyosarcoma. This is an STL file created from DICOM images of his CT scan which may be used for 3D printing. The primary motions of the ankle are dorsiflexion, plantarflexion, inversion, and eversion. However, with the addition of midfoot motion (adduction, and abduction), the foot may supinate (inversion and adduction) or pronate (eversion and abduction). In order to accomplish these motions, muscles outside of the foot (extrinsic) and muscles within the foot (intrinsic) attach throughout the foot, crossing one or more joints. Laterally, the peroneus brevis and tertius attach on the proximal fifth metatarsal to evert the foot. The peroneus longus courses under the cuboid to attach on the plantar surface of the first metatarsal, acting as the primary plantarflexor of the first ray and, secondarily, the foot. Together, these muscles also assist in stabilizing the ankle for patients with deficient lateral ankle ligaments from chronic sprains. Medially, the posterior tibialis inserts on the plantar aspect of the navicular cuneiforms and metatarsal bases, acting primarily to invert the foot and secondarily to plantarflex the foot. The flexor hallucis longus inserts on the base of the distal phalanx of the great toe to plantarflex the great toe, and the flexor digitorum inserts on the bases of the distal phalanges of the lesser four toes, acting to plantarflex the toes. The gastrocnemius inserts on the calcaneus as the Achilles tendon and plantarflexes the foot. Anteriorly, the tibialis anterior inserts on the dorsal medial cuneiform and plantar aspect of the first metatarsal base as the primary ankle dorsiflexor and secondary inverter. The Extensor hallucis longus and extensor digitorum longus insert on the dorsal aspect of the base of the distal phalanges to dorsiflex the great toe and lesser toes, respectively. This model was created from the file STS_014.

    Free

  6. Version 1.0.0

    1 download

    This is the normal right foot and ankle muscle model of a 56-year-old male with right anterior thigh pleomorphic leiomyosarcoma. This is an STL file created from DICOM images of his CT scan which may be used for 3D printing. The primary motions of the ankle are dorsiflexion, plantarflexion, inversion, and eversion. However, with the addition of midfoot motion (adduction, and abduction), the foot may supinate (inversion and adduction) or pronate (eversion and abduction). In order to accomplish these motions, muscles outside of the foot (extrinsic) and muscles within the foot (intrinsic) attach throughout the foot, crossing one or more joints. Laterally, the peroneus brevis and tertius attach on the proximal fifth metatarsal to evert the foot. The peroneus longus courses under the cuboid to attach on the plantar surface of the first metatarsal, acting as the primary plantarflexor of the first ray and, secondarily, the foot. Together, these muscles also assist in stabilizing the ankle for patients with deficient lateral ankle ligaments from chronic sprains. Medially, the posterior tibialis inserts on the plantar aspect of the navicular cuneiforms and metatarsal bases, acting primarily to invert the foot and secondarily to plantarflex the foot. The flexor hallucis longus inserts on the base of the distal phalanx of the great toe to plantarflex the great toe, and the flexor digitorum inserts on the bases of the distal phalanges of the lesser four toes, acting to plantarflex the toes. The gastrocnemius inserts on the calcaneus as the Achilles tendon and plantarflexes the foot. Anteriorly, the tibialis anterior inserts on the dorsal medial cuneiform and plantar aspect of the first metatarsal base as the primary ankle dorsiflexor and secondary inverter. The Extensor hallucis longus and extensor digitorum longus insert on the dorsal aspect of the base of the distal phalanges to dorsiflex the great toe and lesser toes, respectively. This model was created from the file STS_014.

    Free

  7. Version 1.0.0

    0 downloads

    This is my 3D printable model made from a CT scan

    Free

  8. Version 1.0.0

    5 downloads

    This is an anonymized CT scan DICOM dataset to be used for teaching on how to create a 3D printable models.

    Free

  9. Version 1.0.0

    5 downloads

    This is the normal right leg bone model (including foot) of an 82-year-old male. This is an STL file created from DICOM images of his CT scan which may be used for 3D printing. The leg includes the area between the knee and the ankle and houses the tibia and fibula. The proximal tibia includes the medial plateau (which is concave) and the lateral plateau (which is convex). The Proximal tibia has a 7-10 degree posterior slope. On the anterior proximal tibia, the tibial tuberosity, where the patellar tendon attaches. On the anteromedial surface of the tibia is Gerdy's tubercle, where the sartorius, gracilis, and semitendinosus attach. The distal tibia creates the superior and medial (plafond and medial malleolus) of the ankle joint. The proximal fibula is the attachment for the posterolateral corner structures of the knee joint. The peroneal nerve wraps around the fibular neck. The distal fibula is the lateral malleolus and a common site for ankle fractures. This model was created from the file STS_013.

    Free

  10. Version 1.0.0

    1 download

    This is the normal right leg muscle model (including foot) of an 82-year-old male. This is an STL file created from DICOM images of his CT scan which may be used for 3D printing. The lower leg is divided into four muscle compartments: the anterior, lateral, superficial posterior, and deep posterior compartments. The anterior compartment is made from the dorsiflexors, including the tibialis anterior, extensor hallucis longus (EHL), extensor digitorum longus (EDL) and peroneus tertius, which are innervated by the deep peroneal nerve. The lateral compartment includes the peroneus longus and peroneus brevis, which assist in foot eversion and are innervated by the superficial peroneal nerve. The superficial posterior compartment include the gastrocnemius, soleus, and plantaris, which assist in plantarflexion and are innervated by the tibial nerve. The deep posterior compartment is made up of the popliteus, flexor hallucis longus (FHL), flexor digitorum longus (FDL), and tibialis posterior, which mostly assist in plantarflexion and are innervated similarly by the tibial nerve. This file was created from the file STS_013.

    Free

  11. Stratasys is helping to sponsor a randomized clinical trial to determine the effectiveness of 3d printed heart models for pediatric congenital heart surgery. Read the full story here.
  12. Researchers at UC San Diego have successfully 3D printed a network of blood vessels. This is an important step towards 3D printing an entire organ. Read the full story here.
  13. 3D printing technologies have opened up the capabilities for customization in a wide variety of applications in the medical field. Using bio-compatible and drug-contact materials, medical devices can be produced that are perfectly suited for a particular individual. Another trend enabled by 3D printing is mass customization, in that multiple individualized items can be produced simultaneously, saving time and energy while improving manufacturing efficiency. 3D printers are used to manufacture a variety of medical devices, including those with complex geometry or features that match a patient’s unique anatomy. Some devices are printed from a standard design to make multiple identical copies of the same device. Other devices, called patient-matched or patient-specific devices, are created from a specific patient’s imaging data. Commercially available 3D printed medical devices include: Instrumentation (e.g., guides to assist with proper surgical placement of a device) Implants (e.g., cranial plates or hip joints) External prostheses (e.g., hands) Prescription Glasses Hearing Aids In summary, the 3D Printing medical device market looks exciting and promising, Various Reports and surveys suggest the unexpected growth and demand for 3D Printing in medical device industry and it is expected to blossom more but a number of existing application areas for 3D printing in healthcare sector require specialized materials that meet rigid and stringent bio-compatibility standards, Future 3D printing applications for the medical device field will certainly emerge with the development of suitable additional materials for diagnostic and therapeutic use that meet CE and FDA guidelines.
  14. Cardiologists in Aalst, Belgium, 3D printed the hearts of two patients for preprocedural planning in the treatment of arrhythmia (irregular heartbeat). There are different types of arrhythmia and treatment thereof varies. Some conditions don’t require any treatment, while others call for medication or surgical procedures. One minimally invasive procedure is catheter ablation. During this procedure, a catheter delivers high-frequency electrical energy to a small area of tissue inside the heart that causes the abnormal heart rhythm. This energy scars the tissue, thus destroying the electrical pathway that causes the abnormality. Typically, each pathway needs to be disabled individually. Drs. Tom De Potter and Peter Geelen developed a new, more efficient ablation technique to treat arrhythmia. They now can treat the affected tissue in its entirety, rather than pathway by pathway. Given that everyone’s heart anatomy is different and the risks involved in using a new technique, they had their patients’ hearts 3D printed from a CT scan to practice, customize and perfect their technique. For updates on news and new blog entries, follow us on Twitter at @Embodi3D. Photo credit: http://www.hartcentrumaalst.be/nieuws
  15. The 3D printing technology has proven its benefits to the field of medicine. Recently, researchers from the Japanese company Fasotec created realistic 3D printed models of lungs based on the patented technology called Biotexture Wet Models. This particular technology allows surgeons as well as medical students to practice surgical training on almost realistic lungs that do not only have textures similar to real lungs but also comes complete with blood vessels. The reason for the development of realistic 3D printed lungs is to allow students to practice for real life surgical experience. Currently, the 3D printed realistic lungs are used at Jikei University Hospital in Tokyo. The lungs are made by creating the 3D-printed model shells. The shells are hard and empty and then are filled with gel to make up the synthetic replica of human lungs. The doctors then make the final touches to make the model look as real as a human organ as possible. Tomohiro Kinoshita, one of the researchers who developed the Biotexture Wet Models, said that this new innovation in 3D printing lets doctors and students experience the softness of real organs and see them bleed. With the almost realistic experience provided by such a 3D printed organ, both doctors and students will be able to improve their skills even before they go to the operating room. This futuristic technology provided by 3D printing looks very promising and Fasotec is not only geared towards developing realistic lung models but also other organs such as the heart, kidney and liver.
  16. Very few infectious diseases in recent years have commanded the kind of attention and concern that Zika Virus has. Although Zika outbreaks have been reported in Africa, Southeast Asia and other parts of the world since the 1952, recent announcement by the Center for Disease Control and Prevention (CDC) confirming its link with microcephaly has forced everyone to sit up and take notice. The CDC estimates that the current pandemic is widespread with at least 50 countries reporting active Zika transmissions at this time. Most people with Zika virus infection will not have any symptoms though some may experience mild fever, conjunctivitis, muscle and joint pain, and headaches. The virus is primarily transmitted by the Aedes mosquito. However, pregnant women may pass the infection to their babies, which may lead to microcephaly, a neurological condition associated with an abnormally small brain in the infant. The condition can lead to birth defects ranging from hearing loss to poor vision and impaired growth. Prompt diagnosis and treatment of Zika virus infections in pregnant women can, nonetheless, lower the risk of microcephaly to a great extent. Researchers have, therefore, put in a lot of time, money and effort to find a solution, and as always, three-dimensional (3D) medical printing and bioprinting technologies are leading the way. Understanding the Disease To begin with, 3D printing has played a crucial role in conclusively establishing the link between Zika virus and microcephaly. Researchers at John Hopkins Medicine used 3D bioprinting technology to develop realistic models of brain that revealed how the virus infects specialized stem cells in the outer layers of the organ, also known as the cortex. The bioprinted models allowed researchers to study the effects of Zika exposure on fetal brain during different stages of pregnancy. The models are also helping the scientists with drug testing, which is the obvious next stage of their research. Zika Test Kit Engineers at Penn’s School of Engineering and Applied Science, under the leadership of Professor Changchun Liu and Professor Haim Bau, have developed a simple genetic testing device that helps detect Zika virus in saliva samples. It consists of an embedded genetic assay chip that identifies the virus and turns the color of the paper in the 3D printed lid of the device to blue. This can prompt healthcare professionals to send the patient for further testing and to initiate treatment. Unlike other Zika testing techniques, this screening method does not require complex lab equipment. Each device costs about $2, making Zika screening accessible to pregnant women from the poorest parts of the world. Treating Microcephaly The scientists at the Autonomous University of the State of Morelos (UAEM) in Mexico are relying on the additive printing technology to create a microvalve that may help treat microcephaly in infants. The valve reduces the impact of the neurological disease and slows its progression by draining out excessive cerebrospinal fluid associated with this disorder. It can be inserted into the infant brain through a small incision to relieve fluid pressure and provide space for normal development. Researchers estimate the device will be available for patient use by 2017. These examples clearly demonstrate the impact of 3D printing on every aspect of the fight against Zika virus from diagnosing the disease to treating it. The results have been extremely promising, and both researchers and healthcare professionals are immensely hopeful that additive printing technology will help them overcome the infection quickly and effectively.
  17. Version 1.0.0

    13 downloads

    There are four STL files for 3D printing demonstrating a moderate secundum atrial septal defect (ASD) and a mild coarctation. An atrial septal defect is a birth defect of the heart in which there is a hole in the wall (septum) that divides the upper chambers of the heart (atria). A hole can vary in size and may close on its own or may require surgery. If one of these openings does not close, a hole is left, and it is called an atrial septal defect. The hole increases the amount of blood that flows through the lungs and over time, it may cause damage to the blood vessels in the lungs. Damage to the blood vessels in the lungs may cause problems in adulthood, such as high blood pressure in the lungs and heart failure. Other problems may include abnormal heartbeat, and increased risk of stroke. MRI obtained for evaluation of distal arch and pulmonary veins due to findings of pulmonary overcirculation out of proportion to typical ASD pathophysiology. The MRI provided a complete anatomic overview and quantified the right sided enlargement from the 2:1 shunt through the ASD. Due to saturation band nulling of blood returning through the right sided pulmonary veins, there was excellent definition of the ASD due to the "dark" blood mixing with the "bright" blood and outlining the borders of the ASD which transfers to the model very well. Please keep in mind, that the model represents a heart in end-systole rather than diastole. Disclaimer: The available model has been validated to demonstrate the case’s pathologic features on a Z450 3D printer, (3DSystems, Circle Rock Hill, South Carolina)(or other printer as appropriate). While the mask applied to the original DICOM images accurately represents the anatomic features, some anatomic detail may be lost due to thin walled structures or inadequate supporting architecture; while other anatomic detail may be added due to similar limitations resulting in bleeding of modeling materials into small negative spaces. However, intracardiac structures, relationships, and pathologic features represent anatomic findings to scale and in high detail. Credit: The model is provided for distribution on Embodi3D with the permission of the author, pediatric cardiologist Dr. Matthew Bramlet, MD, and is part of the Congenital Heart Defects library. We thank Dr. Bramlet and all others who are working to help children with congenital heart problems lead normal and happy lives. It is distributed by Dr. Bramlet under the Creative Commons license Attribution-NonCommercial-NoDerivs. Please respect the terms of the licensing agreement.

    Free

  18. Version 1.0.0

    14 downloads

    These congenital heart defect STL files demonstrate Partial Anomalous Pulmonary Venous Return (PAPVR). In PAPVR, one or two of the pulmonary veins returns blood to the right atrium instead of the left atrium. This causes oxygen-rich blood to flow back to the lungs instead of on to the rest of the body. Because some oxygen-rich blood is continually flowing between the lungs and the right atrium, the right chambers of the heart may become dilated. Over time, this may cause an abnormal heart rhythm (arrhythmia). In addition, too much blood flow to the lungs may increase the pressure in the lung's blood vessels, leading to a condition called pulmonary hypertension. If only one of the pulmonary veins is affected by the disorder, there may not be any symptoms. If two of the veins are affected, there may be shortness of breath during heavy exercise. Aortic coarctation is also present. Coarctation of the aorta is a narrowing of the aorta, the main blood vessel carrying oxygen-rich blood from the left ventricle of the heart to all of the organs of the body. Coarctation occurs most commonly in a short segment of the aorta just beyond where the arteries to the head and arms take off, as the aorta arches inferiorly toward the chest and abdomen. There are three STL files for 3D printing this model in slices. A whole model STL file is also available for 3D printing. Demonstrated is a bicuspid aortic valve and history of coarctation repair within the first week of life by end to end anastomosis. MRI obtained for evaluation of distal arch. MRI findings: • PAPVR of left upper lobe to innominate vein: Qp:Qs of 1.4:1 • Mild residual narrowing of second transverse segment of the aortic arch. • Moderate post-stenotic dilation of aorta MRI images obtained at end-systole due to tachycardic heart rate during exam. RV End-systolic volume is 36.3 ml. LV End-systolic volume is 30.06 ml. MRI methods: A GE 1.5T HDxt system was used for the 3D HEART sequence which used a 3D respiratory-navigated balanced SSFP (steady state free precession) multi-slab sequence with T2 preparation that provides whole heart coverage with high contrast-to-noise ratio between vessels and myocardium. Due to the relatively fast heart rate of 122 bpm, the fat saturation was turned off to decrease the time needed for the prepatory pulse brining the acquisition window earlier into the cardiac cycle so that it could be centered on the quiescent stage of end systole. The sequence was run with the following parameters: TR 3.4, TE 1.4, Freq 224, Phase 160, RR 8, and fat sat off. Learning: The MRI identified previously un-diagnosed partial anomalous pulmonary venous return. However, the Qp:Qs fell within acceptable left to right shunting of < 1.5:1 and there was insignificant RV, RA enlargement. The MRI evaluation of the coarctation repair revealed a good repair with only mild narrowing, which appeared more severe by echo due to the post-stenotic dilation. Disclaimer: The available model has been validated to demonstrate the case’s pathologic features on a Z450 3D printer, (3DSystems, Circle Rock Hill, South Carolina)(or other printer as appropriate). While the mask applied to the original DICOM images accurately represents the anatomic features, some anatomic detail may be lost due to thin walled structures or inadequate supporting architecture; while other anatomic detail may be added due to similar limitations resulting in bleeding of modeling materials into small negative spaces. However, intracardiac structures, relationships, and pathologic features represent anatomic findings to scale and in high detail. Credit: The model is provided for distribution on Embodi3D with the permission of the author, pediatric cardiologist Dr. Matthew Bramlet, MD, and is part of the Congenital Heart Defects library. We thank Dr. Bramlet and all others who are working to help children with congenital heart problems lead normal and happy lives. It is distributed by Dr. Bramlet under the Creative Commons license Attribution-NonCommercial-NoDerivs. Please respect the terms of the licensing agreement.

    Free

  19. Please note the democratiz3D service was previously named "Imag3D" In this tutorial you will learn how to quickly and easily make 3D printable bone models from medical CT scans using the free online service democratiz3D. The method described here requires no prior knowledge of medical imaging or 3D printing software. Creation of your first model can be completed in as little as 10 minutes. You can download the files used in this tutorial by clicking on this link. You must have a free Embodi3D member account to do so. If you don't have an account, registration is free and takes a minute. It is worth the time to register so you can follow along with the tutorial and use the democratiz3D service. >> DOWNLOAD TUTORIAL FILES AND FOLLOW ALONG << Both video and written tutorials are included in this page. Before we start you'll need to have a copy of a CT scan. If you are interested in 3D printing your own CT scan, you can go to the radiology department of the hospital or clinic that did the scan and ask for the scan to be put on a CD or DVD for you. Figures 1 and 2 show the radiology department at my hospital, called Image Management, and the CDs that they give out. Most radiology departments will have you sign a written release and give you a CD or DVD for free or with a small processing fee. If you are a doctor or other healthcare provider and want to 3D print a model for a patient, the radiology department can also help you. There are multiple online repositories of anonymized CT scans for research that are also available. Figure 1: The radiology department window at my hospital. Figure 2: An example of what a DVD containing a CT scan looks like. This looks like a standard CD or DVD. Step 1: Register for an Embodi3D account If you haven't already done so, you'll need to register for an embodi3d account. Registration is free and only takes a minute. Once you are registered you'll receive a confirmatory email that verifies you are the owner of the registered email account. Click the link in the email to activate your account. The democratiz3D service will use this email account to send you notifications when your files are ready for download. Step 2: Create an NRRD file with Slicer If you haven't already done so, go to slicer.org and download Slicer for your operating system. Slicer is a free software program for medical imaging research. It also has the ability to save medical imaging scans in a variety of formats, which is what we will use it for in this tutorial. Next, launch Slicer. Insert your CD or DVD containing the CT scan into your computer and open the CD with File Explorer or equivalent file browsing application for your operating system. You should find a folder that contains numerous DICOM files in it, as shown in Figure 3. Drag-and-drop the entire DICOM folder onto the Slicer welcome page, as shown in Figure 4. Click OK when asked to load the study into the DICOM database. Click Copy when asked if you want to copy the images into the local database directory. Figure 3: A typical DICOM data set contains numerous individual DICOM files. Figure 4: Dragging and dropping the DICOM folder onto the Slicer application. This will load the CT scan. Once Slicer has finished loading the study, click the save icon in the upper left-hand corner as shown in Figure 5. One of the files in the list will be of type NRRD. make sure that this file is checked and all other files are unchecked. click on the directory button for the NRRD file and select an appropriate directory to save the file. then click Save, as shown in Figure 6. Figure 5: The Save button Figure 6: The Save File box The NRRD file is much better for uploading then DICOM. Instead of having multiple files in a DICOM data set, the NRRD file encapsulates the entire study in a single file. Also, identifiable patient information is removed from the NRRD file. The file is thus anonymized. This is important when sending information over the Internet because we do not want identifiable patient information transmitted. Step 3: Upload the NRRD file to Embodi3D Now go to www.embodi3d.com, click on the democratiz3D navigation menu and select Launch App, as shown in Figure 7. Drag and drop your NRRD file where indicated. While NRRD file is uploading, fill in the "File Name" and "About This File" fields, as shown in Figure 8. Figure 7: Launching the democratiz3D application Figure 8: Uploading the NRRD file and entering basic information To complete basic information about your NRRD file. Do you want it to be private or do you want to share it with the community? Click on the Private File button if the former. If you are planning on sharing it, do you want it to be a free or a paid (licensed) file? Click the appropriate setting. Also select the License Type. If you are keeping the file private, these settings don't matter as the file will remain private. Make sure you accepted the Terms of Use, as shown in Figure 9. Figure 9: Basic information fields about your uploaded NRRD file Next, turn on democratiz3D Processing by selecting the slider under democratiz3D Processing. Make sure the operation CT NRRD to Bone STL is selected. Leave the default threshold of 150 in place. Choose an appropriate quality. Low quality produces small files quickly but the output resolution is low. Medium quality is good for most applications and produces a relatively good file that is not too large. High quality takes the longest to process and produces large output files. Bear in mind that if you upload a low quality NRRD file don't expect the high quality setting to produce a stellar bone model. Medium quality is good enough for most applications. If you wish, you have the option to specify whether you want your output file to be Private or Shared. If you're not sure, click Private. You can always change the visibility of the file later. If you're happy with your settings, click Save & Submit Files. This is shown in Figure 10. Figure 10: Entering the democratiz3D Processing parameters. Step 4: Review Your Completed Bone Model After about 10 to 20 minutes you should receive an email informing you that your file is ready for download. The actual processing time may vary depending on the size and complexity of the file and the load on the processing servers. Click on the link within the email. If you are already on the embodied site, you can access your file by going to your profile. Click your account in the upper right-hand corner and select Profile, as shown in Figure 11. Figure 11: Finding your profile. Your processed file will have the same name as the uploaded NRRD file, except it will end in "– processed". Renders of your new 3D model will be automatically generated within about 6 to 10 minutes. From your new model page you can click "Download this file" to download. If you wish to share your file with the community, you can toggle the privacy setting by clicking Privacy in the lower right-hand corner. You can edit your file or move it from one category to another under the File Actions button on the lower left. These are shown in Figure 12. Figure 12: Downloading, sharing, and editing your new 3D printable model. If you wish to sell your new file, you can change your selling settings under File Actions, Edit Details. Set the file type to be Paid, and specify a price. Please note that your file must be shared in order for other people to see it. This is shown in Figure 13. If you are going to sell your file, be sure you select General Paid File License from the License Type field, or specify your own customized license. For more information about selling files, click here. Figure 13: Making your new file available for sale on the Embodi3D marketplace. That's it! Now you can create your own 3D printable bone models in minutes for free and share or sell them with the click of a button.If you want to download the STL file created in this tutorial, you can download it here. Happy 3D printing!
  20. Physicians across the globe have relied on surgical interventions for centuries to treat complex illnesses and injuries. High quality surgical instruments have played an important role in their success. Nonetheless, healthcare professionals are constantly looking for tools that would improve patient outcomes and minimize the risk of unwanted complications. In recent times, three-dimensional (3D) medical printing and bioprinting technologies have allowed doctors and engineers to develop innovative tools that help perform invasive procedures with greater ease. Robotic Surgical Tools Mechanical engineering students at Brigham Young University (BYU), under the guidance of their professors Barry Howell, Spencer Magleby, and Brian Jensen, combined additive printing technology and the ancient art of Origami to create surgical tools that can fit through 3mm wide incisions. Inside the body, the tools can unfold and expand into complex devices such as D-core tools. Minute incisions allow for quick healing eliminating the need for sutures and scars. The tools are highly precise and effective as well. Researchers at BYU are now collaborating with California-based Intuitive Surgicals to manufacture their products. The company is using 3D printing to develop both the prototypes and the actual tools. The 3D printing technology is also helping Intuitive Surgicals to create instruments with fewer parts making the entire process more cost-effective and stable. The Pathfinder ACL Guide Orthopedic surgeon Dr. Dana Piasecki of the OrthoCarolina Sports Medicine has developed a 3D printed surgical tool to conduct ACL surgeries with improved success. Currently, most surgeons drill a hole in the patient’s tibia to remove the torn anterior cruciate ligament and replace it with a graft. The procedure is painful, and the graft often fails to anchor properly. The Pathfinder ACL Guide, created by Dr. Piasecki in collaboration with Strasys Direct Manufacturing, has a 95 percent chance of placing the graft at the right position and helping it withstand the stress associated with extensive movement. The surgical tool is made from a biocompatible and flexible metal and is significantly cheaper than the existing devices. The Pathfinder ACL Guide has been registered with the FDA as a class I medical device and can now help thousands of amateur and professional athletes to continue playing their game in spite of an ACL tear. Eyelid Wands and Forceps Similarly, Dr. Bret Kotlus, a New York-based cosmetic surgeon, has used 3D printing technology to create customized tools for eyelid surgeries. His stainless steel Eyelid Wand helps surgeons lift excess eyelid skin and point it to various facial structures as per the needs of the patient. The handle of the tool consists of a ruler for accurate measurements. Dr. Kotlus has also developed 3D printed Pinch Blepharoplasty Marking Forceps that allow surgeons to mark excessive skin with a gentle ink. It comes with a round tip and a built-in ruler handle for additional patient comfort. These tools also add some sophistication to the doctor’s office at an affordable price. Close to 50 million surgical inpatient procedures are performed across the United States each year. While recent times have seen a significant improvement in the way these interventions are carried out, a lot can be done to make the process more efficient and safe. This is where 3D printing is bound to make a huge impact in the near future. Sources: Johnson & Johnson Adopts Cutting Edge 3D Printing for the Future of Medical Devices 3d printed eyelid instrument designed by Dr. Kotlus 3D Printed Tool Offers New Option for ACL Surgery Researchers Combine Origami, 3D Printing in Quest for Smaller Surgical Tools
  21. Hello. I own a 3D Printing Service Bureau (imtyris.com). The out put of our 3D printer is a paper model, either plain white, or in millions of colors. I'm looking for someone to work with to develop CT or MRI data into a full color paper model. Dave Jahnz Imtyris 858 354-4200
  22. Examples of historical medical 3D printing on display at RSNA. The green skull is from 1985! We've come a long way since then.
  23. Please note that any references to “Imag3D” in this tutorial should be replaced with “democratiz3D” In this tutorial we will discuss how to share, sell, organize, and reprocess 3D printable medical models you make using the free online Imag3D service from embodi3D. Imag3D is a powerful tool that automatically converts a medical CT scan into a 3D printable file in minutes with minimal user input. It is no longer necessary to master complicated desktop software and spend hours manually segmenting to create a 3D printable model. Learn how to make high quality medical 3D models with Imag3D by following my introductory guide to creating medical 3D printing files and my more advanced 3D printing file processing tutorial. Once you create your medical masterpiece, you can share, sell, organize, or tweak your model to make it perfect. This tutorial will show you how. Resubmit your CT Scan for Reprocessing into Bone STL If you are trying to learn the basics of how to convert CT scans into 3D printable STL models, please see my earlier tutorials on basic creation of 3D printable models and more advanced multiprocessing. If you are not 100% satisfied with the quality of your STL model, you can resubmit the input scan file for repeat processing. To do this, go to the page for your input NRRD file. IMPORTANT: this is the NRRD file you originally uploaded to the website, NOT the STL file that was generated for you by the online service. Since both the original NRRD file and the processed STL file have similar titles, you can tell the difference by noting that the NRRD file you uploaded won't have any thumbnails, Figure 1. In most cases, the processed file will have the word "processed" appended to the file name. Figure 1: Choose the original NRRD file, not the generated STL file. You can find your files underneath your profile, as shown in Figure 2. That will show you your most recent activity, including recently uploaded files. Figure 2: Finding your files under your profile. If you uploaded the file long ago or contribute a lot of content to the site, your uploaded NRRD file may not be among the first content item shown. You can search specifically for your files by clicking on See My Activity under your Profile, and selecting Files from the left hand now bar, as shown in Figures 3 and 4. Figure 3: Showing all your activity. Figure 4: Showing the files you own. Once you have found your original NRRD file, open the file page and select File Actions on the lower left-hand corner, as shown in Figure 5. Choose Edit Details as shown in Figure 6. Figure 5: File Actions – start making changes to your file Figure 6: Edit Details Scroll down until you reach the Imag3D Processing section. Make sure that the Imag3D Processing slider is turned ON. Then, make whatever adjustments you want to the processing parameters Threshold and Quality, as shown in Figure 7. Threshold is the value in Hounsfield units to use when performing the initial segmentation. Quality is a measure of the number of polygons in the output mesh. Low quality is quick to process and generates a small output file. Low quality is suitable for small and geometrically simple structures, such as a patella or single bone. High quality takes longer to process and produces a very large output file, sometimes with millions of polygons. This is useful for very large structures or complex anatomy, such as a model of an entire spine where you wish to capture every crack and crevice of the spine. Medium quality is a good balance and suitable in most cases. Figure 7: Changing the processing parameters. When you're happy with your parameter choices, click Save. The file will now be submitted for reprocessing. In 5 to 15 minutes you should receive an email saying that your file is ready. From this NRRD file, an entirely new STL file will be created using your updated parameters and saved under your account. Sharing your 3D Printing File on embodi3D.com Sharing your file with the embodi3D community is easy. You can quickly share the file by toggling the privacy setting on the file page underneath the File Information box on the lower right, as shown in Figure 8. If this setting says "Shared," then your file is visible and available for download by registered members of the community. If you wish to have more detailed control over how your file is shared, you can edit your file details by clicking on the File Actions button on the lower left-hand side of the file page, also shown in Figure 8. Click on the Edit Details menu item. This will bring you to the file editing page which will allow you to change the Privacy setting (shared versus private), License Type (several Creative Commons and a generic paid file license are available), and file Type (free versus paid). These are shown in detail in Figure 9. Click Save to save your settings. Figure 8: Quick sharing your file, and the File Actions button Figure 9: Setting the file type, privacy, and license type for your file. Sell your Biomedical 3D Printing File and Generate Income If you would like to sell your file and charge a fee for each download, you may do so by making your file a Paid File. If you have a specialized model that there is some demand for, you can generate income by selling your file in the marketplace. From the Edit Details page under File Actions, as shown in Figure 8, scroll down until you see Type. Choose Paid for the Type. Choose the price you wish to sell your file for in the Price field. This is in US dollars. Buyers will use PayPal to purchase the file where they can pay with Paypal funds or credit card. Make sure that the privacy setting is set to Shared. If you list your file for sale but keep it private and invisible to members, you won't sell anything. Finally, make sure you choose an appropriate license for users who will download your file. The General Paid File License is appropriate and most instances, but you have the option to include a customized license if you wish. This is shown in Figure 10. Figure 10: Configuring settings to sell your file The General Paid File License contains provisions appropriate for most sellers. It tells the purchaser of your file that they can download your file and create a single 3D print, but they can't resell your file or make more than one print without paying you additional license fees. All purchasers must agree to the license prior to download. If you wish to have your own customized license terms, you can select customized license and specify your terms in the description of the file. Organize your file by moving it to a new category If you share your file, you should move the file into an appropriate file category to allow people to find it easily. This is quite simple to do. From the file page, select File Actions and choose the Move item, as shown in Figure 11. You will be able to choose any of the file categories. Choose the one that best fits your particular file. Figure 11: Moving your file to a new category. That's it! Now you can share your amazing 3D printable medical models with the world.
  24. Note: This tutorial accompanies a workshop I presented at the 2016 Radiological Society of North America (RSNA) meeting. The workflow and techniques presented in this tutorial and the conference workshop are identical. In this tutorial we will be using two different ways to create a 3-D printable medical model of a head and neck which will be derived from a real contrast-enhanced CT scan. The model will show detailed anatomy of the bones, as well as the veins and arteries. We will independently create this model using two separate methods. First, we will automatically generate the model using the free online service embodi3D.com. Next, we will create the same file using free desktop software programs 3D Slicer and Meshmixer. If you haven't already, please download the associated file pack which contains the files you'll need to follow along with this tutorial. Following along with the actual files used here will make learning these techniques much easier. The file pack is free. You need to be logged into your embodi3D account to download, but registration is also free and only takes a minute. Also, you'll need an embodi3D.com account in order to use the online service. Registration is worth it, so if you haven't already go ahead and register now. >> DOWNLOAD THE FILE PACK NOW << Online Service: embodi3D.com Step 1: Go to the embodi3D.com website and click on the democratiz3D menu item in the naw bar. Click on the "Launch democratizD" link, as shown in Figure 1. Figure 1: Opening the free online 3D model making service service democratiz3D. Step 2: Now you have to upload your imaging file. Drag and drop the file MANIX Angio CT.nrrd from the File Pack, as shown in Figure 2. This contains the CT scan of the head and neck in NRRD file format. If you are using a file other NRRD that provided by the file pack, please be aware the file must contain a CT scan (NOT MRI!) and the file must be in NRRD format. If you don't know how to create an NRRD file, here is a simple tutorial that explains how. Figure 2: Dragging and dropping the NRRD file to start uploading. Step 3: Type in basic information on the file being uploaded, including File name, file description, and whether you want to share the file or keep it private. Bear in mind that this information pertains to the uploaded file, not the file that will be generated by the service. Step 4: Type in basic parameters for file processing. Turn on the processing slider. Here you will enter in basic information about how you would like the file to be processed. Under Operation, select CT NRRD to Bone STL Detailed, as shown in Figure 3. This will convert a CT scan in NRRD format to a bone STL with high detail. You also have the option to create muscle and skin STL files. The standard operation, CT NRRD to Bone STL sacrifices some detail for a smoother output model. Leave the default threshold at 150. Figure 3: Selecting an operation for file conversion. Next, choose the quality of your output file. Low-quality files process quickly and are appropriate for structures with simple geometry. High quality files take longer to process and are appropriate for very complex geometry. The geometry of our model will be quite complex, so choose high quality. This may take a long time to process however, sometimes up to 40 minutes. If you don't wish to wait so long, you can choose medium quality, as shown in Figure 4, and have a pretty decent output file in about 12 minutes or so. Figure 4: Choosing a quality setting. Finally, specify whether you want your processed file to be shared with the community (encouraged) or private and accessible only to you. If you do decide to share you will need to fill out a few items, such as which CreativeCommons license to share under. If you're not sure, the defaults are appropriate for most people. If you do decide to share thanks very much! The 3D printing community thanks you! Click on the submit button and your file will be submitted for processing! Now all you have to do is wait. The service will do all the work for you! Step 5: Download your file. In 5 to 40 minutes you should receive an email indicating that your file is done and is ready for download. Follow the link in the email message or, if you are already on the embodi3D.com website, click on your profile to view your latest activity, including files belonging to you. Open the download page for your file and click on the "Download this file" button to download your newly created STL file! Figure 5: Downloading your newly completed STL file. Desktop software If you haven't already, download 3D Slicer and Meshmixer. Both of these programs are available on Macintosh and Windows platforms. Step 1: Create an STL file with 3D Slicer. Open 3D Slicer. Drag and drop the file MANIX Angio CT.nrrd from the file pack onto the 3D Slicer window. This should load the file into 3D Slicer, as shown in Figure 6. When Slicer asks you to confirm whether you want to add the file, click OK. Figure 6: Opening the NRRD file in 3D Slicer using drag-and-drop. Step 2: Convert the CT scan into an STL file. From within Slicer, open the Modules menu item and choose All Modules, Grayscale Model Maker, as shown in Figure 7. Figure 7: Opening the Grayscale Model Maker module. Next, enter the conversion parameters for Grayscale Model Maker in the parameters window on the left. Under Input Volume select MANIX Angio CT. Under Output Geometry choose "Create new model." Slicer will create a new model with the default name such as "Output Geometry. If you wish to rename this to something more descriptive, choose Rename current model under the same menu. For this tutorial I am calling the model "RSNA model." For Threshold, set the value to 150. Under Decimate, set the value to 0.75. Double check your settings to make sure everything is correct. When everything is filled in correctly click the Apply button, as shown in Figure 8. Slicer will process for about a minute. Figure 8: Filling in the Grayscale Model Maker parameters. Step 3: Save the new model to STL file format. Now it is time to create an STL file from our digital model. Click on the Save button on the upper left-hand corner of the Slicer window. The Save Scene pop-up window is now shown. Find the row that corresponds to the model name you have given the model. In my case it is called "RSNA model." Make sure that the checkbox next to this row is checked, and all other rows are unchecked. Next, under the File Format column make sure to specify STL. Finally, specify the directory that the new STL file is to be saved into. Double check everything. When you are ready, click Saved. This is all shown in Figure 9. Now that you've created an STL file, we need to postprocessing in Meshmixer. Figure 9: Saving your file to STL format. Step 4: Open Meshmixer, and drag-and-drop the newly created STL file onto the Meshmixer window to open it. Once the model opens, you will notice that there are many red dots scattered throughout the model. These represent errors in the mesh and need to be corrected, as shown in Figure 10. Figure 10: Errors in the mesh as shown in Meshmixer. Each red dot corresponds to an error. Step 5: Remove disconnected elements from the mesh. There are many disconnected elements in this model that we do not want in our final model. An example of unwanted mesh are the flat plates on either side of the head from the pillow that was used to secure the head during the CT scan. Let's get rid of this unwanted mesh. First use the select tool and place the cursor over the four head of the model and left click. The area under the cursor should turn orange, indicating that those polygons have been selected, as shown in Figure 11. Figure 11: Selecting a small zone on the forehead. Next, we are going to expand the selection to encompass all geometry that is attached to the area that we currently have selected. Go to the Modify menu item and select Expand to Connected. Alternatively, you can use the keyboard shortcut and select the E key. This operation is shown in Figure 12. Figure 12: Expanding the selection to all connected parts. You will notice that the right clavicle and right scapula have not been selected. This is because these parts are not directly connected to the rest of the skeleton, as shown in Figure 13. We wish to include these in our model, so using the select tool left click on each of these parts to highlight a small area. Then expand the selection to connected again by hitting the E key. Figure 13: The right clavicle and right scapula are not included in the selection because they are not connected to the rest of the skeleton. Individually select these parts and expand the selection again to include them. At this point you should have all the geometry we want included in the model selected in orange, as shown in Figure 14. Figure 14: All the desired geometry is selected in orange Next we are going to delete all the unwanted geometry that is currently unselected. To start this we will first invert the selection. Under the modify menu, select Invert. Alternatively, you can use the keyboard shortcut I, as shown in Figure 15. Figure 15: Inverting the selection. At this point only the undesired geometry should be highlighted in orange, as shown in Figure 16. This unwanted geometry cannot be deleted by going to the Edit menu and selecting Discard. Alternatively you can use the keyboard shortcut X. Figure 16: Only the unwanted geometry is highlighted in orange. This is ready to delete. Step 6: Correcting mesh errors using the Inspector tool. Meshmixer has a nice tool that will automatically fix many mesh errors. Click on the Analysis button and choose Inspector. Meshmixer will now identify all of the errors currently in the mesh. These are indicated by red, blue, and pink balls with lines pointing to the location of the error. As you can see from Figure 17, there are hundreds of errors still within our mesh. We can attempt to auto repair them by clicking on the Auto Repair All button. At the end of the operation most of the errors have been fixed, but if you remain. This can be seen in Figure 18. Figure 17: Errors in the mesh. Most of these can be corrected using the Inspector tool. Figure 18: Only a few errors remain after auto correction with the Inspector tool. Step 7: Correcting the remaining errors using the Remesh tool. Click on the select button to turn on the select tool. Expand the selection to connected parts by choosing Modify, Expand to Connected. The entire model should now be highlighted and origin color. Next under the edit menu choose Remesh, or use the R keyboard shortcut, as shown in Figure 19. This operation will take some time, six or eight minutes depending on the speed of your computer. What remesh does is it recalculates the surface topography of the model and replaces each of the surface triangles with new triangles that are more regular and uniform in appearance. Since our model has a considerable amount of surface area and polygons, the remesh operation takes some time. Remesh also has the ability to eliminate some geometric problems that can prevent all errors from being automatically fixed in Inspector. Figure 19: Using the Remesh tool. Step 8: Fixing the remaining errors using the Inspector tool. Once the remesh operation is completed we will go back and repeat Step 6 and run the Inspector tool again. Click on Analysis and choose Inspector. Inspector will highlight the errors. Currently there are only two, as shown in Figure 20. These two remaining errors can be easily auto repair using the Auto Repair All button. Go ahead and click on this. Figure 20: running the Inspector tool again. At this point the model is now completed and ready for 3D printing as shown in Figure 21. The mesh is error-free and ready to go! Congratulations! Figure 21: The final, error-free model ready for 3D printing. Conclusion Complex bone and vascular models, such as the head and neck model we created in this tutorial, can be created using either the free online service at embodi3D.com or using free desktop software. Each approach has its benefits. The online service is easier to use, faster, and produces high quality models with minimal user input. Additionally, multiple models can be processed simultaneously so it is possible to batch process multiple files at once. The desktop approach using 3D Slicer and Meshmixer requires more user input and thus more time, however the user has greater control over individual design decisions about the model. Both methods are viable for creating high quality 3D printable medical models. Thank you very much for reading this tutorial. Please share your medical 3D printing designs on the embodi3D.com website. Happy 3D printing!