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Muscular tumors and sarcomas

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Soft tissue sarcomas and other tumors involving the musculature.

23 files

  1. Free

    Right Medial Thigh Undifferentiated Pleomorphic Malignant Fibrous Histiocytoma 3D Printable STL File Converted from CT Scan

    This model is the right thigh muscle rendering of a 49-year-old male with a right medial thigh undifferentiated pleomorphic malignant fibrous histiocytoma (MFH). The patient underwent neoadjuvant radiotherapy, surgery, and adjuvant chemotherapy treatment and was found to have a high-grade lesion at the time of diagnosis. Metastases to his lungs were also found at diagnosis. The patient is still living with the disease at 2 years since diagnosis. This is an STL file created from DICOM images of his CT scan which may be used for 3D printing.
     
    Undifferentiated pleomorphic MFH has more recently been classified as Undifferentiated Pleomorphic Sarcoma. This is the most common soft tissue sarcoma in late adulthood, commonly occurring between 55 to 80 years old and most commonly in Caucasian males. Clinically, it presents as a slowly growing mass in the extremities. Biopsy of the lesion demonstrates, as its name implies, an undifferentiated and pleomorphic appearance. Pleomorphism is the pathologic description of cells and nuclei with variability in size, shape, and staining, which is characteristic of a malignant neoplasm. “Undifferentiated” means that the tissue does not appear like an identifiable tissue structure. Treatment consists of wide resection and radiation. Chemotherapy is added in cases of metastasis, most commonly to the lung. Five-year survival is between 35-60% depending on the grade of tumor and metastases.
     
    This model was created from the file STS_021.

    1 download

       (0 reviews)

    0 comments

    Updated

  2. Free

    Right Medial Thigh Undifferentiated Pleomorphic Malignant Fibrous Histiocytoma 3D Printable STL File Converted from CT Scan

    This model is the bilateral lower extremity muscle rendering of a 49-year-old male with a right medial thigh undifferentiated pleomorphic malignant fibrous histiocytoma (MFH). The patient underwent neoadjuvant radiotherapy, surgery, and adjuvant chemotherapy treatment and was found to have a high-grade lesion at the time of diagnosis. Metastases to his lungs were also found at diagnosis. The patient is still living with the disease at 2 years since diagnosis. This is an STL file created from DICOM images of his CT scan which may be used for 3D printing.
     
    Undifferentiated pleomorphic MFH has more recently been classified as Undifferentiated Pleomorphic Sarcoma. This is the most common soft tissue sarcoma in late adulthood, commonly occurring between 55 to 80 years old and most commonly in Caucasian males. Clinically, it presents as a slowly growing mass in the extremities. Biopsy of the lesion demonstrates, as its name implies, an undifferentiated and pleomorphic appearance. Pleomorphism is the pathologic description of cells and nuclei with variability in size, shape, and staining, which is characteristic of a malignant neoplasm. “Undifferentiated” means that the tissue does not appear like an identifiable tissue structure. Treatment consists of wide resection and radiation. Chemotherapy is added in cases of metastasis, most commonly to the lung. Five-year survival is between 35-60% depending on the grade of tumor and metastases.
     
    This model was created from the file STS_021.

    2 downloads

       (0 reviews)

    0 comments

    Updated

  3. Free

    Right Medial Thigh Undifferentiated Pleomorphic Malignant Fibrous Histiocytoma 3D Printable STL File Converted from CT Scan

    This model is the right thigh muscle rendering of a 49-year-old male with a right medial thigh undifferentiated pleomorphic malignant fibrous histiocytoma (MFH). The patient underwent neoadjuvant radiotherapy, surgery, and adjuvant chemotherapy treatment and was found to have a high grade lesion at the time of diagnosis. Metastases to his lungs were also found at diagnosis. The patient is still living with the disease at 2 years since diagnosis. This is an STL file created from DICOM images of his CT scan which may be used for 3D printing.
     
    Undifferentiated pleomorphic MFH has more recently been classified as Undifferentiated Pleomorphic Sarcoma. This is the most common soft tissue sarcoma in late adulthood, commonly occurring between 55 to 80 years old and most commonly in Caucasian males. Clinically, it presents as a slowly growing mass in the extremities. Biopsy of the lesion demonstrates, as its name implies, an undifferentiated and pleomorphic appearance. Pleomorphism is the pathologic description of cells and nuclei with variability in size, shape, and staining, which is characteristic of a malignant neoplasm. “Undifferentiated” means that the tissue does not appear like an identifiable tissue structure. Treatment consists of wide resection and radiation. Chemotherapy is added in cases of metastasis, most commonly to the lung. Five-year survival is between 35-60% depending on the grade of tumor and metastases.
     
    This model was created from the file STS_021.
     

    1 download

       (0 reviews)

    0 comments

    Updated

  4. Free

    Muscles of the body in a 60 year old woman with a right buttocks myxofibroma (tumor)

    This 3D printable STL file contains a model of the torso a 60 year old woman was derived from a real medical CT scan. The patient has a tumor (myxofibroma) of the left buttocks. The detailed musculature of the body is clearly shown.
    This model was created using the democratiz3D free online 3D model creation service.
    STS007

    7 downloads

       (0 reviews)

    0 comments

    Updated

  5. Free

    Left Thigh Dedifferentiated Liposarcoma 3D Printable Muscle STL File Converted from CT Scan

    These images are the isolated left thigh tumor muscle renderings of an 82 year old male with a dedifferentiated liposarcoma in the anterior compartment of the left thigh. This is an STL file created from DICOM images of his CT scan which may be used for 3D printing.
     
    Liposarcomas are the second most common soft tissue sarcoma in adults, occurring more commonly in males between the ages of 50 and 80 years old. They present as a slow growing, painless mass typically located in the extremities, with the thigh being the most common location. Multiple variants of liposarcomas exist, but the dedifferentiated type is a high-grade sarcoma. Dedifferentiated liposarcomas are typically located adjacent to a well-differentiated lipomatous lesion. The incidence of pulmonary metastasis increases with grade. Therefore, work up of the lesion consists of MRI, biopsy through the area of future resection, CT of the chest, abdomen and pelvis to rule out metastases. Treatment consists of radiation and wide surgical resection but chemotherapy agents are being developed to target chromosomal abnormalities associated with certain well-differentiated and dedifferentiated liposarcomas.  This patient received radiation and resection of the tumor and has not had a metastasis or recurrence in 4.5 years.
     
    This model came from the file STS_013.

    2 downloads

       (0 reviews)

    0 comments

    Updated

  6. Free

    Left Thigh Dedifferentiated Liposarcoma Bilateral Legs Muscle 3D Printable STL File Converted from CT Scan

    These images are the bilateral leg muscle renderings of an 82 year old male with a dedifferentiated liposarcoma in the anterior compartment of the left thigh. This is an STL file created from DICOM images of his CT scan which may be used for 3D printing.
     
    Liposarcomas are the second most common soft tissue sarcoma in adults, occurring more commonly in males between the ages of 50 and 80 years old. They present as a slow growing, painless mass typically located in the extremities, with the thigh being the most common location. Multiple variants of liposarcomas exist, but the dedifferentiated type is a high-grade sarcoma. Dedifferentiated liposarcomas are typically located adjacent to a well-differentiated lipomatous lesion. The incidence of pulmonary metastasis increases with grade. Therefore, work up of the lesion consists of MRI, biopsy through the area of future resection, CT of the chest, abdomen, and pelvis to rule out metastases. Treatment consists of radiation and wide surgical resection but chemotherapy agents are being developed to target chromosomal abnormalities associated with certain well-differentiated and dedifferentiated liposarcomas.  This patient received radiation and resection of the tumor and has not had a metastasis or recurrence in 4.5 years.
     
    This figure came from the file STS_013.

    1 download

       (0 reviews)

    0 comments

    Updated

  7. Free

    Left Groin Leiomyosarcoma 3D Printable STL File Converted From CT Scan

    This 3D model represents a case of high grade leiomyosarcoma implicating the left groin region of a 24 years old female. The patient was treated by surgical excision follower by chemotherapy as well as radiotherapy.   A cross sectional CT image is attached showing the lesion in axial, coronal and sagittal planes.   Leiomyosarcoma (LMS) is a very rare malignant neoplasm that arises from smooth muscle cells and is considered to be the malignant extension of leiomyoma. Leiomyosarcoma is classified under soft tissue tumours and represents around 8% of all soft tissue malignant tumours.   Common locations affected by leiomyosarcoma are: the uterus, retroperitoneum, stomach, oesophagus, small intestine and generally anywhere with smooth muscles.   Leiomyosarcoma appears heterogeneous in CT with common central attenuation representing necrosis.   This 3D model was created from the file STS_036
     
    The source CT scan used to create this model can be found here.
     

    6 downloads

       (0 reviews)

    0 comments

    Updated

  8. Free

    Right Anterior Thigh Pleomorphic Leiomyosarcoma 3D Printable STL File Converted from CT Scan

    This model is the right thigh muscle rendering of a 56 year old male with a pleomorphic leiomyosarcoma of the anterior compartment of the right thigh. The patient underwent neoadjuvant radiotherapy, surgery, and adjuvant chemotherapy treatment and was found to have an intermediate grade lesion at the time of diagnosis.  However, the tumor metastasized to his lungs, and the patient died 2.5 years after diagnosis. This is an STL file created from DICOM images of his CT scan which may be used for 3D printing.
     
    Leiomyosarcomas are aggressive soft tissue malignancies that are thought to arise from the smooth muscle cells lining small blood vessels. Pleomorphism is the pathologic description of cells and nuclei with variability in size, shape and staining, which is characteristic of a malignant neoplasm. Pleomorphic leiomyosarcoma is an aggressive form of leiomyosarcoma, accounting for approximately 10% of these tumors. The mean age of occurrence is 58 years old, with a range from 31-89 years. These usually occur in the extremities, but may also present in the retroperitoneum/abdominal cavity, chest/abdominal wall, and, occasionally, the scalp. On biopsy, the definition of pleomorphic leiomyosarcoma is the presence of pleomorphic cells in at last two-thirds of the cut section and at least one section of positive staining for smooth muscle. Treatment is early wide resection of the primary lesion and neo-adjuvant or adjuvant chemotherapy and radiation. Tumors may metastasize to the lung. A large primary tumor and presence in the retroperitoneal cavity are poor predictive factors, and about 65% of patients succumb to the disease.
     
    This model was created from the file STS_014.

    5 downloads

       (0 reviews)

    0 comments

    Updated

  9. Free

    Sarcoma of the left calf

    This 3D printable STL file contains a model of the muscles of the left calf and knee was derived from a real medical CT scan. This 60 year old woman has a soft tissue sarcoma involving the left calf muscle (gastrocnemius) which results in a somewhat bulging appearance of this muscle.
    This model was created using the democratiz3D free online 3D model creation service.
    STS_010

    2 downloads

       (0 reviews)

    0 comments

    Updated

  10. Free

    Right hand sarcoma, a 3D printable medical file converted from a CT scan DICOM set of a 48-year old female

    This is a 3D printable medical file of a CT scan DICOM dataset of a 48-year old female that was presented by right hand swelling, pathological examination revealed it to be undifferentiated malignant fibrous histiocystosis of high grade of malignancy. 28 days prior to the pathological examination, the patient underwent MRI. 30 days after the diagnosis had been made, the patient underwent PET scan. Her treatment plan was combined surgical excision/radiotherapy. after 1082 days of follow up, the patient showed no evidence of disease.(STS_019)

    1 download

       (0 reviews)

    0 comments

    Updated

  11. Free

    Right Shoulder CT scan - undifferentiated pleomorphic spindle cell sarcoma

    CT scan showing a case of undifferentiated pleomorphic spindle cell sarcoma implicating the right parascapular region of a 61 years old male. The patient represented with lung metastasis and was treated by surgical excision follower by chemotherapy as well as radiotherapy.   The CT scan is derived from case file STS_037   The 3D bone model created from this scan can be reviewed at: The 3D muscle model created from this scan can be reviewed at:  The 3D skin model created from this scan can be reviewed at: 

    1 download

       (0 reviews)

    0 comments

    Updated

  12. Free

    Right Anterior Thigh Pleomorphic Leiomyosarcoma 3D Printable STL File Converted from CT Scan

    This model is the bilateral thigh muscle rendering of a 56 year old male with a pleomorphic leiomyosarcoma of the anterior compartment of the right thigh. The patient underwent neoadjuvant radiotherapy, surgery, and adjuvant chemotherapy treatment and was found to have an intermediate grade lesion at the time of diagnosis.  However, the tumor metastasized to his lungs, and the patient died 2.5 years after diagnosis. This is an STL file created from DICOM images of his CT scan which may be used for 3D printing.
     
    Leiomyosarcomas are aggressive soft tissue malignancies that are thought to arise from the smooth muscle cells lining small blood vessels. Pleomorphism is the pathologic description of cells and nuclei with variability in size, shape and staining, which is characteristic of a malignant neoplasm. Pleomorphic leiomyosarcoma is an aggressive form of leiomyosarcoma, accounting for approximately 10% of these tumors. The mean age of occurrence is 58 years old, with a range from 31-89 years. These usually occur in the extremities, but may also present in the retroperitoneum/abdominal cavity, chest/abdominal wall, and, occasionally, the scalp. On biopsy, the definition of pleomorphic leiomyosarcoma is the presence of pleomorphic cells in at last two-thirds of the cut section and at least one section of positive staining for smooth muscle. Treatment is early wide resection of the primary lesion and neo-adjuvant or adjuvant chemotherapy and radiation. Tumors may metastasize to the lung. A large primary tumor and presence in the retroperitoneal cavity are poor predictive factors, and about 65% of patients succumb to the disease.
     
    This model was created from the file STS_014.

    2 downloads

       (0 reviews)

    0 comments

    Updated

  13. Free

    Right Shoulder - undifferentiated pleomorphic spindle cell sarcoma - Muscle Model STL file from converted CT scan

    This 3D model represents a case of undifferentiated pleomorphic spindle cell sarcoma implicating the right parascapular region of a 61 years old male. The patient represented with lung metastasis and was treated by surgical excision follower by chemotherapy as well as radiotherapy. A cross sectional CT image is attached showing the lesion in axial, coronal and sagittal planes.   Unfortunately pleomorphic undifferentiated sarcoma has an aggressive biological behaviour and a poor prognosis.   Pleomorphic undifferentiated sarcomas can occur almost anywhere in the body, they have a predilection for the retroperitoneum and proximal extremities. They are usually confined to the soft tissues, but occasionally may arise in or from bone.   This 3D model was created from the file STS_037   The original CT examination can be reviewed at:   The 3D bone model created from this scan can be reviewed at: The 3D skin model created from this scan can be reviewed at:   

    1 download

       (0 reviews)

    0 comments

    Updated

  14. Free

    Left thigh sarcome, a 3D printable medical file converted from a CT scan DICOM dataset of a 78-year old female patient

    This is a 3D printable STL medical file converted from a CT scan DICOM dataset of a 78-year old female that was presented by left thigh swelling, Pathological examination revealed it to be malignant fibrous histiocytosis ( pleomorphic sarcoma) of high grade malignancy. The patient underwent MRI and PET scan 7 and 8 days after the pathological examination respectively. The patient underwent combined surgical excision/radiotherapy. 66 days later the patient developed regional recurrence. After 377 days of follow up, The patient was alive with disease. ( STS-020)

    4 downloads

       (0 reviews)

    0 comments

    Updated

  15. Free

    Left pelvic(posterior aspect) leiomyosarcoma, converted from a CT scan DICOM dataset of a 68-year old male

    This is a 3D printable medical file converted from a CT scan DICOM dataset of a 68-year old male presented by a swelling at the posterior aspect of the left pelvic region(notice the contour bulge at the posterior aspect of the left side). Histopathological examination revealed the swelling to be leiomyosarcoma of intermediate grade of malignancy. His work up included MRI and PET scan 3 and 24 days after the pathological examination respectively. His treatment plan was a combined radiotherapy/surgical resection of the tumor. 96 days later, the patient developed lung metastasis. He died after 607 days.(STS-018)

    2 downloads

       (0 reviews)

    0 comments

    Updated

  16. Free

    Left thigh extraskeletal Ewing, a 3D printable medical file converted from a CT scan DICOM dataset of 54-year old male patient

    This is a 3D printable STL file converted from a CT scan DICOM dataset of a 54-year old male patient that was presented by a left thigh swelling. Histopathological examination revealed it to be extra-skeletal Ewing sarcoma of high grade of malignancy. 10 days prior to the diagnosis, the patient underwent MRI. 21 days after the diagnosis had been made the patient underwent PET scan examination as a part of his metastatic workup.His treatment plan was a combined chemotherapy/surgical resection of the tumor. 525 days later, the patient developed lung metastasis. 265 days later, the patient died.(STS-017)

    1 download

       (0 reviews)

    0 comments

    Updated

  17. Free

    Left thigh sarcoma, a 3D printable medical file converted from a CT scan DICOM dataset of a 78-year old female patient

    This is a 3D printable STL medical file converted from a CT scan DICOM dataset of a 78-year old female that was presented by left thigh swelling( note the difference in contour between both sides), pathological examination revealed it to be malignant fibrous histiocytosis ( pleomorphic sarcoma) of high grade malignancy. The patient underwent MRI and PET scan 7 and 8 days after the pathological examination respectively. Her treatment plan was combined surgical excision and radiotherapy. 66 days later she developed regional recurrence. After 377 days of follow up, The patient was alive with disease. ( STS-020)

    3 downloads

       (0 reviews)

    0 comments

    Updated

  18. Free

    Right Medial Thigh Undifferentiated Pleomorphic Malignant Fibrous Histiocytoma 3D Printable STL File Converted from CT Scan

    This model is the bilateral thigh rendering of a 49-year-old male with a right medial thigh undifferentiated pleomorphic malignant fibrous histiocytoma (MFH). The patient underwent neoadjuvant radiotherapy, surgery, and adjuvant chemotherapy treatment and was found to have a high-grade lesion at the time of diagnosis. Metastases to his lungs were also found at diagnosis. The patient is still living with the disease at 2 years since diagnosis. This is an STL file created from DICOM images of his CT scan which may be used for 3D printing.
     
    Undifferentiated pleomorphic MFH has more recently been classified as Undifferentiated Pleomorphic Sarcoma. This is the most common soft tissue sarcoma in late adulthood, commonly occurring between 55 to 80 years old and most commonly in Caucasian males. Clinically, it presents as a slow growing mass in the extremities. Biopsy of the lesion demonstrates, as its name implies, an undifferentiated and pleomorphic appearance. Pleomorphism is the pathologic description of cells and nuclei with variability in size, shape and staining, which is characteristic of a malignant neoplasm. “Undifferentiated” means that the tissue does not appear like an identifiable tissue structure. Treatment consists of wide resection and radiation. Chemotherapy is added in cases of metastasis, most commonly to the lung. Five-year survival is between 35-60% depending on grade of tumor and metastases.
     
    This model was created from the file STS_021.

    1 download

       (0 reviews)

    0 comments

    Updated

  19. Free

    Right buttock epithelioid sarcoma with vascular differentiation 3D Printable STL File Converted From CT Scan

    This 3D model represents a case of epithelioid sarcoma with vascular differentiation implicating the right buttock region of a 57 years old female. The patient represented with lung metastasis and was treated by surgical excision follower by chemotherapy as well as radiotherapy.
    A cross sectional CT image is attached showing the lesion in axial, coronal and sagittal planes.   Epithelioid sarcoma is a rare soft tissue tumor with unclear histogenesis that is often mistaken for a chronic inflammatory process or necrotizing granuloma due to its innocuous presentation as well as unusual both epithelial and mesenchymal differentiation.
    This 3D model was created from the file STS_040   The original CT examination can be reviewed at: The 3D bone model created from this scan can be reviewed at:

    2 downloads

       (0 reviews)

    0 comments

    Updated

  20. Free

    Left Anterior Thigh Myxoid Fibrosarcoma 3D Printable STL File Converted from CT Scan

    This model is the left thigh muscle rendering of a 65-year-old male with left thigh myxoid fibrosarcoma. At the time of diagnosis, the patient had metastases to his lungs. The patient therefore underwent neoadjuvant radiotherapy, surgery, and adjuvant chemotherapy and was found to have an intermediate grade lesion at the time of diagnosis. The patient is still living with the metastatic disease at 2.5 years since diagnosis. This is an STL file created from DICOM images of his CT scan which may be used for 3D printing.
     
    Myxoid fibrosarcoma (or myxoid MFH) is the most common subtype of MFH, at about 10%-20% of cases. Clinically, the tumor presents as a deep, slow-growing, painless mass. It is located more commonly in the lower extremities and retroperitoneum. Imaging on MRI demonstrates a mass with low signal intensity on T1-weighting imaging, and high signal intensity on T2-weighted imaging. On histology, a myxoid background is present with a storiform (or cartwheel) pattern seen on low-power imaging, seen in fibrosarcomas. A “myxoid background” is composed of a clear, mucoid substance. Treatment includes radiation, wide surgical resection, and chemotherapy in selected cases.  However, the 5-year survival is 50%-60% depending on size, grade, depth and presence of metastasis.
     
    The term “malignant fibrous histiocytoma” was coined in the 1960s by Margaret R. Murray when histology a sarcoma demonstrated an appearance like histiocytes, with characteristics of phagocytosis and a pleomorphic pattern. With further research, this entity was identified to have a wider range of appearances with a fibrous characteristic. Today, these sarcomas are known as “pleomorphic sarcomas.”
     
    Recently, a change in the understanding of soft tissue tumors has purported that MFH is not a specific type of cancer, but a common morphologic pattern shared by unrelated tumors. One school of thought states that this morphologic pattern is shared by tumors as a common final pathway in cancer progression whereas another school of thought believes that true pleomorphic sarcomas are the result of a transformation from mesenchymal stem cells. Future research into understanding the pathway of these sarcomas and progression will help to target specific therapies and, hopefully, eventual cures.
     
    This model was created from the file STS_022.

    1 download

       (0 reviews)

    0 comments

    Updated

  21. Free

    Left Lower Extremity with Left Anterior Thigh Myxoid Fibrosarcoma 3D Printable STL File Converted from CT Scan

    This model is the left lower extremity muscle rendering of a 65-year-old male with left thigh myxoid fibrosarcoma. At the time of diagnosis, the patient had metastases to his lungs. The patient therefore underwent neoadjuvant radiotherapy, surgery, and adjuvant chemotherapy and was found to have an intermediate grade lesion at the time of diagnosis. The patient is still living with the metastatic disease at 2.5 years since diagnosis. This is an STL file created from DICOM images of his CT scan which may be used for 3D printing.
     
    Myxoid fibrosarcoma (or myxoid MFH) is the most common subtype of MFH, at about 10%-20% of cases. Clinically, the tumor presents as a deep, slow-growing, painless mass. It is located more commonly in the lower extremities and retroperitoneum. Imaging on MRI demonstrates a mass with low signal intensity on T1-weighting imaging, and high signal intensity on T2-weighted imaging. On histology, a myxoid background is present with a storiform (or cartwheel) pattern seen on low-power imaging, seen in fibrosarcomas. A “myxoid background” is composed of a clear, mucoid substance. Treatment includes radiation, wide surgical resection, and chemotherapy in selected cases.  However, the 5-year survival is 50%-60% depending on size, grade, depth and presence of metastasis.
     
    The term “malignant fibrous histiocytoma” was coined in the 1960s by Margaret R. Murray when histology a sarcoma demonstrated an appearance like histiocytes, with characteristics of phagocytosis and a pleomorphic pattern. With further research, this entity was identified to have a wider range of appearances with a fibrous characteristic. Today, these sarcomas are known as “pleomorphic sarcomas.”
     
    Recently, a change in the understanding of soft tissue tumors has purported that MFH is not a specific type of cancer, but a common morphologic pattern shared by unrelated tumors. One school of thought states that this morphologic pattern is shared by tumors as a common final pathway in cancer progression whereas another school of thought believes that true pleomorphic sarcomas are the result of a transformation from mesenchymal stem cells. Future research into understanding the pathway of these sarcomas and progression will help to target specific therapies and, hopefully, eventual cures.
     
    This model was created from the file STS_022.

    3 downloads

       (0 reviews)

    0 comments

    Updated

  22. Free

    Left Anterior Thigh Myxoid Fibrosarcoma 3D Printable STL File Converted from CT Scan

    This model is the bilateral thigh muscle rendering of a 65-year-old male with left thigh myxoid fibrosarcoma. At the time of diagnosis, the patient had metastases to his lungs. The patient therefore underwent neoadjuvant radiotherapy, surgery, and adjuvant chemotherapy and was found to have an intermediate grade lesion at the time of diagnosis. The patient unfortunately died 9.5 months after diagnosis. This is an STL file created from DICOM images of his CT scan which may be used for 3D printing.
     
    Myxoid fibrosarcoma (or myxoid MFH) is the most common subtype of MFH, at about 10%-20% of cases. Clinically, the tumor presents as a deep, slow-growing, painless mass. It is located more commonly in the lower extremities and retroperitoneum. Imaging on MRI demonstrates a mass with low signal intensity on T1-weighting imaging, and high signal intensity on T2-weighted imaging. On histology, a myxoid background is present with a storiform (or cartwheel) pattern seen on low-power imaging, seen in fibrosarcomas. A “myxoid background” is composed of a clear, mucoid substance. Treatment includes radiation, wide surgical resection, and chemotherapy in selected cases.  However, the 5-year survival is 50%-60% depending on size, grade, depth and presence of metastasis.
     
    The term “malignant fibrous histiocytoma” was coined in the 1960s by Margaret R. Murray when histology a sarcoma demonstrated an appearance like histiocytes, with characteristics of phagocytosis and a pleomorphic pattern. With further research, this entity was identified to have a wider range of appearances with a fibrous characteristic. Today, these sarcomas are known as “pleomorphic sarcomas.”
     
    Recently, a change in the understanding of soft tissue tumors has purported that MFH is not a specific type of cancer, but a common morphologic pattern shared by unrelated tumors. One school of thought states that this morphologic pattern is shared by tumors as a common final pathway in cancer progression whereas another school of thought believes that true pleomorphic sarcomas are the result of a transformation from mesenchymal stem cells. Future research into understanding the pathway of these sarcomas and progression will help to target specific therapies and, hopefully, eventual cures.
     
    This model was created from the file STS_023.

    2 downloads

       (0 reviews)

    0 comments

    Updated

  23. Free

    Left Anterior Thigh Myxoid Fibrosarcoma 3D Printable STL File Converted from CT Scan

    This model is the left thigh muscle rendering of a 65-year-old male with left thigh myxoid fibrosarcoma. At the time of diagnosis, the patient had metastases to his lungs. The patient therefore underwent neoadjuvant radiotherapy, surgery, and adjuvant chemotherapy and was found to have an intermediate grade lesion at the time of diagnosis. The patient unfortunately died 9.5 months after diagnosis. This is an STL file created from DICOM images of his CT scan which may be used for 3D printing.
     
    Myxoid fibrosarcoma (or myxoid MFH) is the most common subtype of MFH, at about 10%-20% of cases. Clinically, the tumor presents as a deep, slow-growing, painless mass. It is located more commonly in the lower extremities and retroperitoneum. Imaging on MRI demonstrates a mass with low signal intensity on T1-weighting imaging, and high signal intensity on T2-weighted imaging. On histology, a myxoid background is present with a storiform (or cartwheel) pattern seen on low-power imaging, seen in fibrosarcomas. A “myxoid background” is composed of a clear, mucoid substance. Treatment includes radiation, wide surgical resection, and chemotherapy in selected cases.  However, the 5-year survival is 50%-60% depending on size, grade, depth and presence of metastasis.
     
    The term “malignant fibrous histiocytoma” was coined in the 1960s by Margaret R. Murray when histology a sarcoma demonstrated an appearance like histiocytes, with characteristics of phagocytosis and a pleomorphic pattern. With further research, this entity was identified to have a wider range of appearances with a fibrous characteristic. Today, these sarcomas are known as “pleomorphic sarcomas.”
     
    Recently, a change in the understanding of soft tissue tumors has purported that MFH is not a specific type of cancer, but a common morphologic pattern shared by unrelated tumors. One school of thought states that this morphologic pattern is shared by tumors as a common final pathway in cancer progression whereas another school of thought believes that true pleomorphic sarcomas are the result of a transformation from mesenchymal stem cells. Future research into understanding the pathway of these sarcomas and progression will help to target specific therapies and, hopefully, eventual cures.
     
    This model was created from the file STS_023.

    6 downloads

       (0 reviews)

    0 comments

    Updated

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    • Here is an article on the benefits of using 3D printed temporal bones for surgical training   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703115/
    • Valchanov,   I downloaded the file and took a look. I see right ventricular hypertrophy, a large VSD, pulmonary valve atresia/stenosis and an overriding aorta that is also on the right side. I think this is Tetrology of Fallot. It is a cool scan! Dr. Mike
    • Hello Can you give me some background information about the health condition of the patient? The set is excellent, but there is something really wrong with the anatomy of this heart. I want to model it properly.
    • The whole time I was thinking that I'm doing something wrong, because it's impossible for a TAAA to be that big. This was beyond everything I ever saw for 22 years of medical education and experience. But yes, it's THAT big. I segmented the lumen, I added 2 cm margin around it to create a hollow shell, then I added the media of the aneurysmic sack and all the atherosclerotic plaques for extra realism. There was a part of the sack, which went into one of the perihepatic space, but I removed it, b
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    • 3D printing is a technology that is constantly evolving, especially among medical professionals who are converting medical CT scans into 3D-printed anatomical models. Patient-specific models with anatomical fidelity created from imaging dataset have the potential to significantly improve the knowledge and skills of a new generation of surgeons. In terms of research and education, 3D-printed anatomical models have proven to be a major benefit in helping students and researchers gain first-hand knowledge of specific conditions and the human anatomy. Check this!   https://www.embodi3d.com/blogs/entry/403-dicom-to-stl-files-and-other-medical-scans-uploaded-to-embodi3d®/  
    • How many grams of polymer this thorax took (scaffold included)?
    • We'd like to share some of the best medical 3D printing models, as well as a few detailed examples that garnered the attention of embodi3D® users. 3D-printable STL files like these are helping physicians and medical students to further their understanding of complex diagnoses and treatments — and your contributions are a big part of embodi3D's continued success.   https://www.embodi3d.com/blogs/entry/394-great-3d-medical-printing-files-recently-shared-on-embodi3d®/
    • Medical 3D printing can be used to create centimeter- to sub-millimeter-accurate models. These include the hearts, lungs, kidney, and colon featured in this week's Top Ten, but can be used to create just about any type of 3D organ or tissue model. Check the top 10 and share your comments.   https://www.embodi3d.com/blogs/entry/393-top-10-organ-stl-files-downloaded-on-embodi3d®/
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